Cost-benefit Analysis of DNA Marker Selection in Sweet Cherry Breeding

Marker-assisted selection allows researchers to more quickly and efficiently select and breed crops with desired traits and genes as compared to conventional breeding techniques. This technology can require costly investments for reagents, machinery, and labor. Molecular marker research on crops with short breeding cycles such as corn, wheat, and potato has revealed a direct relationship between the time saved and cost of the technology. In order to improve understanding of the cost-effectiveness of using markers for crops with long breeding cycles, we conducted a cost-benefit analysis incorporating marker-assisted selection in a sweet cherry breeding program. The annual operational costs of a sweet cherry breeding program were used for the simulated breeding models. The itemized costs of production and cost per unit were estimated for each stage of the breeding model and used to compare the costs with and without the use of marker-assisted selection technology. Simulations were conducted using different selection rates at the stage of greenhouse establishment: intense (12.5%), moderate (20%), and mild (25%). Break-even selection rates where the cost-savings with the use of markers equal the additional costs incurred by using markers were determined. The break-even point simulation was then compared to the simulation of a traditional breeding program without marker technologies. The results have important implications for breeding programs that are considering whether to implement marker-assisted breeding technology.