Analysis of Serum Marker Proteins in Hepatitis C Patients As Affected By Neem (Azadiracta indica)

Fifty patients infected with hepatitis C virus were subjected to iserum proteins analysis which was inhibited by Azadirecta indica extracts in comparison with normal control subjects in order to determine specific marker proteins in blood serum. In serum of HCV patients increased values of alanine transaminase, alkaline phosphatase, bilirubin, total protein, calcium, potassium and sodium were observed as compare to healthy individuals. However, serum albumin was not much fluctuated. Electrophoresis of serum samples of HCV patients showed that 14 Kda and 30 Kda proteins were expressed at high level while in normal healthy individuals 19 Kda protein was observed predominantly. In serum samples of both HCV and healthy individuals 60 Kda protein was also observed. The serum analysis results were further confirmed on high pressure liquid chromatography analysis. The proteins expressed in serum of HCV patients may be further validated in different populations.Fifty patients infected with hepatitis C virus were subjected to iserum proteins analysis which was inhibited by Azadirecta indica extracts in comparison with normal control subjects in order to determine specific marker proteins in blood serum. In serum of HCV patients increased values of alanine transaminase, alkaline phosphatase, bilirubin, total protein, calcium, potassium and sodium were observed as compare to healthy individuals. However, serum albumin was not much fluctuated. Electrophoresis of serum samples of HCV patients showed that 14 Kda and 30 Kda proteins were expressed at high level while in normal healthy individuals 19 Kda protein was observed predominantly. In serum samples of both HCV and healthy individuals 60 Kda protein was also observed. The serum analysis results were further confirmed on high pressure liquid chromatography analysis. The proteins expressed in serum of HCV patients may be further validated in different populations.